Triflic acid-catalyzed cascade cyclization of arenyl enynes via acetylene-cation cyclization and Friedel-Crafts type reaction

Tienan Jin; Junichi Uchiyama; Masafumi Himuro; Yoshinori Yamamoto

doi:10.1016/j.tetlet.2010.10.094

Triflic acid-catalyzed cascade cyclization of arenyl enynes via acetylene-cation cyclization and Friedel-Crafts type reaction

Tienan Jin, Junichi Uchiyama, Masafumi Himuro, Yoshinori Yamamoto

SCI - Research and Analytical Center for Giant Molecules

Research output: Contribution to journal › Article › peer-review

26 Citations (Scopus)

Abstract

A novel triflic acid-catalyzed cascade cyclization of arenyl 1,7-enynes through acetylene-cation cyclization followed by Friedel-Crafts reaction has been described. Various fused poly carbocycles can be obtained in good to high yields under mild reaction conditions.

Original language	English
Pages (from-to)	2069-2071
Number of pages	3
Journal	Tetrahedron Letters
Volume	52
Issue number	17
DOIs	https://doi.org/10.1016/j.tetlet.2010.10.094
Publication status	Published - 2011 Apr 27

Keywords

Acetylene-cation cyclization
Arenyl enynes
Friedel-Crafts type reaction
Fused carbocycles
Triflic acid

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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title = "Triflic acid-catalyzed cascade cyclization of arenyl enynes via acetylene-cation cyclization and Friedel-Crafts type reaction",

abstract = "A novel triflic acid-catalyzed cascade cyclization of arenyl 1,7-enynes through acetylene-cation cyclization followed by Friedel-Crafts reaction has been described. Various fused poly carbocycles can be obtained in good to high yields under mild reaction conditions.",

keywords = "Acetylene-cation cyclization, Arenyl enynes, Friedel-Crafts type reaction, Fused carbocycles, Triflic acid",

author = "Tienan Jin and Junichi Uchiyama and Masafumi Himuro and Yoshinori Yamamoto",

note = "Funding Information: This work was financially supported by a Grant-in Aid for Young Scientists (B) from Japan Society for Promotion of Science (JSPS). ",

year = "2011",

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doi = "10.1016/j.tetlet.2010.10.094",

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T1 - Triflic acid-catalyzed cascade cyclization of arenyl enynes via acetylene-cation cyclization and Friedel-Crafts type reaction

AU - Jin, Tienan

AU - Uchiyama, Junichi

AU - Himuro, Masafumi

AU - Yamamoto, Yoshinori

N1 - Funding Information: This work was financially supported by a Grant-in Aid for Young Scientists (B) from Japan Society for Promotion of Science (JSPS).

PY - 2011/4/27

Y1 - 2011/4/27

N2 - A novel triflic acid-catalyzed cascade cyclization of arenyl 1,7-enynes through acetylene-cation cyclization followed by Friedel-Crafts reaction has been described. Various fused poly carbocycles can be obtained in good to high yields under mild reaction conditions.

AB - A novel triflic acid-catalyzed cascade cyclization of arenyl 1,7-enynes through acetylene-cation cyclization followed by Friedel-Crafts reaction has been described. Various fused poly carbocycles can be obtained in good to high yields under mild reaction conditions.

KW - Acetylene-cation cyclization

KW - Arenyl enynes

KW - Friedel-Crafts type reaction

KW - Fused carbocycles

KW - Triflic acid

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JF - Tetrahedron Letters

SN - 0040-4039

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ER -

Triflic acid-catalyzed cascade cyclization of arenyl enynes via acetylene-cation cyclization and Friedel-Crafts type reaction

Abstract

Keywords

ASJC Scopus subject areas

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