Abstract
(Chemical Equation Presented) A new triazole-linked analogue of DNA ( TLDNA) has been designed and synthesized using click chemistry. The chain elongation reaction using copper-catalyzed Huisgen cycloaddition was successful and gave the artificial oligonucleotide that formed a stable double strand with the complementary strand of natural DNA.
Original language | English |
---|---|
Pages (from-to) | 3729-3732 |
Number of pages | 4 |
Journal | Organic letters |
Volume | 10 |
Issue number | 17 |
DOIs | |
Publication status | Published - 2008 Dec 1 |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry