Trends in antimicrobial resistance of streptococcus pneumoniae in Japan

R. Yoshida, M. Kaku, S. Kohno, K. Ishida, R. Mizukane, H. Takemura, H. Tanaka, T. Usui, K. Tomono, H. Koga, K. Hara

Research output: Contribution to journalArticlepeer-review

57 Citations (Scopus)


A total of 184 isolates of Streptococcus pneumoniae were recovered from the sputa of patients over a 5-year period in the Nagasaki area and were examined. A total of 30 strains were resistant to penicillin (MIC, ≥0.10 μg/ml), 13 of which belonged to serotype 19B. These strains showed decreased susceptibility to other antimicrobial agents. Vancomycin, cefpirome, and imipenem were the most active agents tested.

Original languageEnglish
Pages (from-to)1196-1198
Number of pages3
JournalAntimicrobial agents and chemotherapy
Issue number5
Publication statusPublished - 1995
Externally publishedYes

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases


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