Transverse myelopathy with renovascular hypertension caused by fibromuscular dysplasia

M. Matsuzaki, I. Nakashima, Y. Shiga, K. Fujihara, Y. Itoyama

Research output: Contribution to journalArticlepeer-review


An 18-year-old woman developed subacute transverse myelopathy with renovascular hypertension, hyperlipidemia, and proteinuria. Spinal magnetic resonance imaging (MRI) showed an intra-spinal cord lesion with severe spinal cord swelling at the C 2-Th 2 level. Increased plasma and cerebrospinal fluid interleukin-8 (IL-8) levels and the presence of serum anti-neutrophil cytoplasmic antibody (ANCA) suggested the existence of an ischemic lesion due to vasculitis. Administration of corticosteroids ameliorated the clinical symptoms and MRI findings. Renovascular angiogram revealed the presence of fibromuscular dysplasia(FMD) at the left renal artery but no malformation was found at the cervical arteries. We discussed the possibility of relationships between myelopathy, FMD, IL-8, and ANCA.

Original languageEnglish
Pages (from-to)859-862
Number of pages4
JournalBrain and Nerve
Issue number9
Publication statusPublished - 2001


  • Antineutrophil cytoplasmic antibody (ANCA)
  • Fibromuscular dysplasia (FMD)
  • Interleukin-8
  • Renovascular hypertension
  • Transverse myelopathy

ASJC Scopus subject areas

  • Neuroscience(all)


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