Transient directing groups for the most straightforward arylation of C(sp ³ )-H bonds

Transition-metal catalyzed C(sp ³ )-H functionalization is one of the most attractive reaction because it enables straightforward and economical syntheses of organic compounds. In the past decades, C(sp ³ )-H functionalization approaches using directing groups have been developed, however, their stoichiometric installation and removal of directing groups limit efficiency. Recently, a "transient directing group" strategy has been emerged as the solution of this program. This review highlights recent advances in C(sp ³ -H arylation using a "transient directing group".