Transfer hydrogenation reaction of ketones and formic acid under hydrothermal conditions without a catalyst

Zheng Shen, Yalei Zhang, Xuefei Zhou, Bing Wu, Jianglin Cao, Fangming Jin

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The hydrothermal experiments with ketones and formic acid showed that the hydrogen transfer reduction of ketones can be conducted with formic acid as a hydride donor in the presence of NaOH at 300 °C. The yield of alcohols was considerably higher at a much lower ratio of hydrogen source to ketones than the traditional Meerwein-Ponndorf-Verley reduction, reaching 60% for isopropanol from acetone and 70% for lactic acid from pyruvic acid. Water molecules as a catalyst may directly participate in the transition state by making a hydrogen-bond ring network with the substrate molecules.

Original languageEnglish
Title of host publication2nd International Symposium on Aqua Science, Water Resource and Low Carbon Energy
Pages356-359
Number of pages4
DOIs
Publication statusPublished - 2010 Dec 1
Event2nd International Symposium on Aqua Science, Water Resource and Low Carbon Energy - Sanya, China
Duration: 2009 Dec 72009 Dec 10

Publication series

NameAIP Conference Proceedings
Volume1251
ISSN (Print)0094-243X
ISSN (Electronic)1551-7616

Other

Other2nd International Symposium on Aqua Science, Water Resource and Low Carbon Energy
Country/TerritoryChina
CitySanya
Period09/12/709/12/10

Keywords

  • Formic acid
  • Hydrothermal reaction
  • Ketone
  • Transfer hydrogenation reduction

ASJC Scopus subject areas

  • Physics and Astronomy(all)

Fingerprint

Dive into the research topics of 'Transfer hydrogenation reaction of ketones and formic acid under hydrothermal conditions without a catalyst'. Together they form a unique fingerprint.

Cite this