Toxicological effects of polycyclic aromatic hydrocarbon quinones contaminated in diesel exhaust particles

Yoshito Kumagai, Keiko Taguchi

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Accumulated epidemiological and animal studies have suggested that prolonged exposure to ambient particulate matter (PM) is associated with an increased risk of cardiovascular disease and pulmonary dysfunction. While diesel exhaust particles (DEP) contain large variety of compounds, polycyclic aromatic hydrocarbons (PAHs) are a dominant component contaminated in DEP. This article reviews effects of two PAH quinones, 9,10-phenanthraquinone (9,10-PQ) and 1,2-naphthoquinone (1,2-NQ), on vascular and respiratory systems.

Original languageEnglish
Pages (from-to)28-35
Number of pages8
JournalAsian Journal of Atmospheric Environment
Volume1
Issue number1
DOIs
Publication statusPublished - 2007 Dec
Externally publishedYes

Keywords

  • Diesel exhaust particle
  • Oxidative stress
  • Polycyclic aromatic hydrocarbon
  • Quinone
  • Vascular dysfunction

ASJC Scopus subject areas

  • Environmental Science(all)
  • Atmospheric Science

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