Toward the total synthesis of goniodomin A, an actin-targeting marine polyether macrolide: Convergent synthesis of the C15-C36 Segment

Tomoyuki Saito, Haruhiko Fuwa, Makoto Sasaki

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Stereoselective convergent synthesis of the C15-C36 segment of goniodomin A, an actin-targeting marine polyether macrolide natural product, has been achieved. The present synthesis features palladium(0)-catalyzed, copper(I)-mediated Liebeskind-Srogl cross-coupling as the fragment assembly process.

Original languageEnglish
Pages (from-to)5274-5277
Number of pages4
JournalOrganic letters
Volume11
Issue number22
DOIs
Publication statusPublished - 2009 Dec 3

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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