Abstract
The first total synthesis of (±)-trachyspic acid, a tumor cell heparanase inhibitor, was accomplished based on Cr(II)/Ni(II)-mediated reaction of the aldehyde containing the citric acid moiety and the long-chain triflate, and the relative configuration of this natural product was determined.
Original language | English |
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Pages (from-to) | 857-859 |
Number of pages | 3 |
Journal | Organic letters |
Volume | 5 |
Issue number | 6 |
DOIs | |
Publication status | Published - 2003 Mar 20 |
Externally published | Yes |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry