Total Synthesis of Neu5Ac via Alkylation of 2-Alkoxy-2-cyanoacetate with a Sugar-Derived Bromide

T. Takahashi, H. Tsukamoto, M. Kurosaki, H. Yamada

Research output: Contribution to journalArticle

22 Citations (Scopus)

Abstract

N-Acetylneuraminic acid was synthesized via alkylation of 2-alkoxy-2-cyanoacetate anion, an acyl anion equivalent of alkyl glyoxylate, with a sugar-derived bromide prepared from D-glycero-D-gulo-heptose-1,4-lactone.

Original languageEnglish
Pages (from-to)1065-1066
Number of pages2
JournalSynlett
Volume1997
Issue number9
DOIs
Publication statusPublished - 1997 Jan 1

ASJC Scopus subject areas

  • Organic Chemistry

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