Total synthesis of (±)-lepadiformine a via radical translocation-cyclization reaction

Manabu Fujitani; Masami Tsuchiya; Kentaro Okano; Kiyosei Takasu; Masataka Ihara; Hidetoshi Tokuyama

doi:10.1055/s-0029-1219389

Total synthesis of (±)-lepadiformine a via radical translocation-cyclization reaction

Manabu Fujitani, Masami Tsuchiya, Kentaro Okano, Kiyosei Takasu, Masataka Ihara, Hidetoshi Tokuyama

PHA - Molecular Pharmaceutical Science

Research output: Contribution to journal › Article › peer-review

29 Citations (Scopus)

Abstract

A total synthesis of (±)-lepadiformine A was accomplished through construction of the 1-azaspiro[4.5]decane skeleton by a sequential radical translocation-cyclization reaction.

Original language	English
Article number	U11109ST
Pages (from-to)	822-826
Number of pages	5
Journal	Synlett
Issue number	5
DOIs	https://doi.org/10.1055/s-0029-1219389
Publication status	Published - 2010

Keywords

Cyclization
Domino reaction
Natural products
Radical reaction
Total synthesis

ASJC Scopus subject areas

Organic Chemistry

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10.1055/s-0029-1219389

Cite this

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title = "Total synthesis of (±)-lepadiformine a via radical translocation-cyclization reaction",

abstract = "A total synthesis of (±)-lepadiformine A was accomplished through construction of the 1-azaspiro[4.5]decane skeleton by a sequential radical translocation-cyclization reaction.",

keywords = "Cyclization, Domino reaction, Natural products, Radical reaction, Total synthesis",

author = "Manabu Fujitani and Masami Tsuchiya and Kentaro Okano and Kiyosei Takasu and Masataka Ihara and Hidetoshi Tokuyama",

year = "2010",

doi = "10.1055/s-0029-1219389",

language = "English",

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journal = "Synlett",

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T1 - Total synthesis of (±)-lepadiformine a via radical translocation-cyclization reaction

AU - Fujitani, Manabu

AU - Tsuchiya, Masami

AU - Okano, Kentaro

AU - Takasu, Kiyosei

AU - Ihara, Masataka

AU - Tokuyama, Hidetoshi

PY - 2010

Y1 - 2010

N2 - A total synthesis of (±)-lepadiformine A was accomplished through construction of the 1-azaspiro[4.5]decane skeleton by a sequential radical translocation-cyclization reaction.

AB - A total synthesis of (±)-lepadiformine A was accomplished through construction of the 1-azaspiro[4.5]decane skeleton by a sequential radical translocation-cyclization reaction.

KW - Cyclization

KW - Domino reaction

KW - Natural products

KW - Radical reaction

KW - Total synthesis

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U2 - 10.1055/s-0029-1219389

DO - 10.1055/s-0029-1219389

M3 - Article

AN - SCOPUS:77749283834

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JO - Synlett

JF - Synlett

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M1 - U11109ST

ER -

Total synthesis of (±)-lepadiformine a via radical translocation-cyclization reaction

Abstract

Keywords

ASJC Scopus subject areas

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