Abstract
Advancing alkaloid synthesis: (+)-Haplophytine (see structure) was the target of a total synthesis featuring a highly stereoselective intramolecular Mannich reaction, Friedel-Crafts alkylation, oxidative rearrangement, and Fischer indole synthesis.
Original language | English |
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Pages (from-to) | 7600-7603 |
Number of pages | 4 |
Journal | Angewandte Chemie - International Edition |
Volume | 48 |
Issue number | 41 |
DOIs | |
Publication status | Published - 2009 Sep 28 |
Keywords
- Alkaloids
- Mannich reaction
- Natural products
- Rearrangement
- Total synthesis
ASJC Scopus subject areas
- Catalysis
- Chemistry(all)