Total synthesis of (-)-dihydrocorynantheol using bicyclo[3.2.1]octenone chiral building block

Ayako Tosaka, Shinichiro Ito, Norio Miyazawa, Masatoshi Shibuya, Kunio Ogasawara, Yoshiharu Iwabuchi

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

The diastereocontrolled synthesis of (-)-dihydrocorynantheol from a bicyclo[3.2.l]octane chiral building block has been achieved by employing a tandem retro-aldol-Pictet-Spengler reaction-C-3 epimerization sequence as the key step.

Original languageEnglish
Pages (from-to)153-159
Number of pages7
JournalHeterocycles
Volume70
Publication statusPublished - 2006 Dec 31

ASJC Scopus subject areas

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

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    Tosaka, A., Ito, S., Miyazawa, N., Shibuya, M., Ogasawara, K., & Iwabuchi, Y. (2006). Total synthesis of (-)-dihydrocorynantheol using bicyclo[3.2.1]octenone chiral building block. Heterocycles, 70, 153-159.