Total synthesis of (-)-conophylline and (-)-conophyllidine

Yuki Han-Ya, Hidetoshi Tokuyama, Tohru Fukuyama

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

Double take: The total syntheses of the title compounds were accomplished in a highly convergent manner. The approach features the regio- and diastereoselective Polonovski-Potier-type reaction for the coupling of two aspidosperma skeletons and the formation of the dihydrofuran ring. Troc=2,2,2-trichloroethoxycarbonyl.

Original languageEnglish
Pages (from-to)4884-4887
Number of pages4
JournalAngewandte Chemie - International Edition
Volume50
Issue number21
DOIs
Publication statusPublished - 2011 May 16

Keywords

  • alkaloids
  • cascade reactions
  • heterocycles
  • natural products
  • total synthesis

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

Fingerprint Dive into the research topics of 'Total synthesis of (-)-conophylline and (-)-conophyllidine'. Together they form a unique fingerprint.

  • Cite this