@article{a5129f29e3fe44a1810c3ca5110d4139,
title = "Total synthesis of allixin; an anti-tumor promoter from garlic",
abstract = "The first synthesis of allixin, an anti-tumor promoter from garlic Allium sativum L., is described the highly oxidized γ-pyrone moiety was synthesized via a 2-methylene tetrahydropyran derivative.",
author = "Hirokazu Arimoto and Shigehiro Asano and Daisuke Uemura",
note = "Funding Information: key step is an oxidation of 2-methylene tetrahydropyran derivative to dihydropyrone. The synthesis will allow access to a variety of side chain analogs, which would give mechanistic insight to the tumor promotion mechanism. Aelmowledgments. This work was financially supported by the Grant-in-Aid for Scientific Research from Ministry of Education, Science and Culture, Japan.",
year = "1997",
month = nov,
day = "3",
doi = "10.1016/S0040-4039(97)10072-7",
language = "English",
volume = "38",
pages = "7761--7762",
journal = "Tetrahedron Letters",
issn = "0040-4039",
publisher = "Elsevier Limited",
number = "44",
}