Total synthesis and determination of the absolute configuration of FD-838, a naturally occurring azaspirobicyclic product

Yujiro Hayashi; Kuppusamy Sankar; Hayato Ishikawa; Yuriko Nozawa; Kazutoshi Mizoue; Hideaki Kakeya

doi:10.1016/j.bmcl.2009.03.154

Total synthesis and determination of the absolute configuration of FD-838, a naturally occurring azaspirobicyclic product

Yujiro Hayashi, Kuppusamy Sankar, Hayato Ishikawa, Yuriko Nozawa, Kazutoshi Mizoue, Hideaki Kakeya

Research output: Contribution to journal › Article › peer-review

20 Citations (Scopus)

Abstract

The first asymmetric total synthesis of FD-838, a naturally occurring azaspirobicyclic product, has been accomplished allowing determination of its absolute stereochemistry.

Original language	English
Pages (from-to)	3863-3865
Number of pages	3
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	19
Issue number	14
DOIs	https://doi.org/10.1016/j.bmcl.2009.03.154
Publication status	Published - 2009 Jul 15
Externally published	Yes

Keywords

Absolute configuration
FD-838
Total synthesis

ASJC Scopus subject areas

Biochemistry
Molecular Medicine
Molecular Biology
Pharmaceutical Science
Drug Discovery
Clinical Biochemistry
Organic Chemistry

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10.1016/j.bmcl.2009.03.154

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Total synthesis and determination of the absolute configuration of FD-838, a naturally occurring azaspirobicyclic product. / Hayashi, Yujiro; Sankar, Kuppusamy; Ishikawa, Hayato; Nozawa, Yuriko; Mizoue, Kazutoshi; Kakeya, Hideaki.

In: Bioorganic and Medicinal Chemistry Letters, Vol. 19, No. 14, 15.07.2009, p. 3863-3865.

Research output: Contribution to journal › Article › peer-review

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abstract = "The first asymmetric total synthesis of FD-838, a naturally occurring azaspirobicyclic product, has been accomplished allowing determination of its absolute stereochemistry.",

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AU - Nozawa, Yuriko

AU - Mizoue, Kazutoshi

AU - Kakeya, Hideaki

N1 - Funding Information: This work was supported by a Grant-in Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology, Government of Japan.

PY - 2009/7/15

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Total synthesis and determination of the absolute configuration of FD-838, a naturally occurring azaspirobicyclic product

Abstract

Keywords

ASJC Scopus subject areas

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