Total synthesis and determination of the absolute configuration of FD-838, a naturally occurring azaspirobicyclic product

Yujiro Hayashi; Kuppusamy Sankar; Hayato Ishikawa; Yuriko Nozawa; Kazutoshi Mizoue; Hideaki Kakeya

doi:10.1016/j.bmcl.2009.03.154

Total synthesis and determination of the absolute configuration of FD-838, a naturally occurring azaspirobicyclic product

Yujiro Hayashi, Kuppusamy Sankar, Hayato Ishikawa, Yuriko Nozawa, Kazutoshi Mizoue, Hideaki Kakeya

Research output: Contribution to journal › Article › peer-review

20 Citations (Scopus)

Abstract

The first asymmetric total synthesis of FD-838, a naturally occurring azaspirobicyclic product, has been accomplished allowing determination of its absolute stereochemistry.

Original language	English
Pages (from-to)	3863-3865
Number of pages	3
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	19
Issue number	14
DOIs	https://doi.org/10.1016/j.bmcl.2009.03.154
Publication status	Published - 2009 Jul 15
Externally published	Yes

Keywords

Absolute configuration
FD-838
Total synthesis

ASJC Scopus subject areas

Biochemistry
Molecular Medicine
Molecular Biology
Pharmaceutical Science
Drug Discovery
Clinical Biochemistry
Organic Chemistry

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10.1016/j.bmcl.2009.03.154

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title = "Total synthesis and determination of the absolute configuration of FD-838, a naturally occurring azaspirobicyclic product",

abstract = "The first asymmetric total synthesis of FD-838, a naturally occurring azaspirobicyclic product, has been accomplished allowing determination of its absolute stereochemistry.",

keywords = "Absolute configuration, FD-838, Total synthesis",

author = "Yujiro Hayashi and Kuppusamy Sankar and Hayato Ishikawa and Yuriko Nozawa and Kazutoshi Mizoue and Hideaki Kakeya",

note = "Funding Information: This work was supported by a Grant-in Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology, Government of Japan. ",

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journal = "Bioorganic and Medicinal Chemistry Letters",

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AU - Hayashi, Yujiro

AU - Sankar, Kuppusamy

AU - Ishikawa, Hayato

AU - Nozawa, Yuriko

AU - Mizoue, Kazutoshi

AU - Kakeya, Hideaki

N1 - Funding Information: This work was supported by a Grant-in Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology, Government of Japan.

PY - 2009/7/15

Y1 - 2009/7/15

N2 - The first asymmetric total synthesis of FD-838, a naturally occurring azaspirobicyclic product, has been accomplished allowing determination of its absolute stereochemistry.

AB - The first asymmetric total synthesis of FD-838, a naturally occurring azaspirobicyclic product, has been accomplished allowing determination of its absolute stereochemistry.

KW - Absolute configuration

KW - FD-838

KW - Total synthesis

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ER -

Total synthesis and determination of the absolute configuration of FD-838, a naturally occurring azaspirobicyclic product

Abstract

Keywords

ASJC Scopus subject areas

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