Total synthesis and determination of the absolute configuration of FD-838, a naturally occurring azaspirobicyclic product

Yujiro Hayashi, Kuppusamy Sankar, Hayato Ishikawa, Yuriko Nozawa, Kazutoshi Mizoue, Hideaki Kakeya

Research output: Contribution to journalArticlepeer-review

19 Citations (Scopus)

Abstract

The first asymmetric total synthesis of FD-838, a naturally occurring azaspirobicyclic product, has been accomplished allowing determination of its absolute stereochemistry.

Original languageEnglish
Pages (from-to)3863-3865
Number of pages3
JournalBioorganic and Medicinal Chemistry Letters
Volume19
Issue number14
DOIs
Publication statusPublished - 2009 Jul 15

Keywords

  • Absolute configuration
  • FD-838
  • Total synthesis

ASJC Scopus subject areas

  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Pharmaceutical Science
  • Drug Discovery
  • Clinical Biochemistry
  • Organic Chemistry

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