Abstract
(Chemical Equetion Presentation) The first total synthesis of (-)-idesolide was achieved via organocatalytic, enantioselective oxidative kinetic resolution (OKR) using (1S,4S)4-Bn-1-Bu-AZADO- and AZADO-catalyzed dimerization of (S)-(-)-methyl 1-hydroxy-6-oxo-2-cyclohexenecarboxylate. The absolute configuration of (-)-idesolide Is determined to be 2R,2' S, 3aS,7aR.
Original language | English |
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Pages (from-to) | 980-983 |
Number of pages | 4 |
Journal | Organic letters |
Volume | 12 |
Issue number | 5 |
DOIs | |
Publication status | Published - 2010 Mar 5 |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry