Abstract
Total syntheses of leuconodine B, melodinine E, and leuconoxine were accomplished via a divergent route. The [5.5.6.6]diazafenestrane skeleton was constructed from an indole-3-acetamide derivative via DMDO oxidation to hydroxylindolenine, TMSOTf/2,6-lutidine mediated cyclic aminal formation, and diastereoseletive ring-closing metathesis of a triene derivative.
Original language | English |
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Pages (from-to) | 2526-2529 |
Number of pages | 4 |
Journal | Organic letters |
Volume | 16 |
Issue number | 9 |
DOIs | |
Publication status | Published - 2014 May 2 |
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry