Background: It is controversial whether cerebral deficits other than frank stroke develop after total aortic arch replacement using hypothermic circulatory arrest (HCA) with antegrade selective cerebral perfusion (SCP). Objectives: We investigated neuropsychological functions in patients who received total aortic arch replacement using deep HCA with SCP. Methods: Eleven patients who underwent elective total arch replacement using deep HCA with antegrade SCP were included. Cognitive functions of the patients were evaluated at baseline, and 3 weeks and 6 months after the aortic arch surgery. Results: The performance of cognitive tests did not change 3 weeks after surgery, except for the attention/ calculation task of the Mini-Mental State Examination (MMSE). Six months after surgery, the decline in score for the attention/calculation task in the MMSE had reversed and the score for this task as well as for all other tests had returned to baseline levels. Conclusion: Long-lasting cognitive deficits other than frank stroke may not develop after total arch replacement surgery using deep HCA with SCP.
- Antegrade selective cerebral perfusion
- Cognitive function
- Deep hypothermic circulatory
- Total aortic arch replacement
ASJC Scopus subject areas
- Pulmonary and Respiratory Medicine
- Cardiology and Cardiovascular Medicine