Tomographic image reconstruction using x-ray phase information

Atsushi Momose, Tohoru Takeda, Yuji Itai, Keiichi Hirano

Research output: Chapter in Book/Report/Conference proceedingConference contribution

16 Citations (Scopus)

Abstract

We have been developing phase-contrast x-ray computed tomography (CT) to make possible the observation of biological soft tissues without contrast enhancement. Phase-contrast x-ray CT requires for its input data the x-ray phase-shift distributions or phase-mapping images caused by an object. These were measured with newly developed fringe-scanning x-ray interferometry. Phase-mapping images at different projection directions were obtained by rotating the object in an x-ray interferometer, and were processed with a standard CT algorithm. A phase-contrast x-ray CT image of a nonstained cancerous tissue was obtained using 17.7 keV synchrotron x rays with 12 micrometer voxel size, although the size of the observation area was at most 5 mm. The cancerous lesions were readily distinguishable from normal tissues. Moreover, fine structures corresponding to cancerous degeneration and fibrous tissues were clearly depicted. It is estimated that the present system is sensitive down to a density deviation of 4 mg/cm 3.

Original languageEnglish
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsRichard L. Van Metter, Jacob Beutel
Pages674-684
Number of pages11
Publication statusPublished - 1996 Jan 1
Externally publishedYes
EventMedical Imaging 1996: Physics of Medical Imaging - Newport Beach, CA, USA
Duration: 1996 Feb 111996 Feb 13

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume2708
ISSN (Print)0277-786X

Other

OtherMedical Imaging 1996: Physics of Medical Imaging
CityNewport Beach, CA, USA
Period96/2/1196/2/13

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

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  • Cite this

    Momose, A., Takeda, T., Itai, Y., & Hirano, K. (1996). Tomographic image reconstruction using x-ray phase information. In R. L. Van Metter, & J. Beutel (Eds.), Proceedings of SPIE - The International Society for Optical Engineering (pp. 674-684). (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 2708).