Tissue coagulation imaging based on Bi-plane RF cross-correlation during high intensity focused ultrasound therapy

Takashi Azuma, Ken Ichi Kawabata, Rei Asami, Shin Ichiro Umemura

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Therapy monitoring based on echo-time-shift imaging during high intensity focused ultrasound (HIFU) treatment was described. The echo shift estimated by radio frequency (RF) correlation between adjacent frames is potentially useful for mapping coagulation and tissue temperature. B-mode images are also useful for real-time monitoring, but cannot show the denatured region formed below the boiling point. Echo-shift images are, however, can. To identify each contribution of reversible and irreversible change, we used a bi-plane ultrasound imaging and a laser displacement meter to detect tissue expansion and velocity change independently. Tissue expansion was mapped using ultrasound echo shift and laser measurement with a split HIFU beam in an in vitro experiment. Expansion ratio was about 5%, and this value was larger than estimated value on the basis of thermal effects. Since the expansion remained after cooling, it was suggested that echo-shift imaging could detect region in which coagulation occurred below the boiling temperature.

Original languageEnglish
Title of host publication2009 IEEE International Ultrasonics Symposium and Short Courses, IUS 2009
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages1769-1772
Number of pages4
ISBN (Print)9781424443895
DOIs
Publication statusPublished - 2009
Event2009 IEEE International Ultrasonics Symposium, IUS 2009 - Rome, Italy
Duration: 2009 Sep 202009 Sep 23

Publication series

NameProceedings - IEEE Ultrasonics Symposium
ISSN (Print)1051-0117

Other

Other2009 IEEE International Ultrasonics Symposium, IUS 2009
Country/TerritoryItaly
CityRome
Period09/9/2009/9/23

ASJC Scopus subject areas

  • Acoustics and Ultrasonics

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