Time course changes in cytoskeletal structures of cultured endothelial cells exposed to shear stress.

K. Ookawa, M. Sato, N. Ohshima

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)

Abstract

Changes in patterns of microfilament distribution were analyzed using cultured porcine aortic endothelial cells under shear flow. Within the elongated endothelial cells after shear flow exposure (20 dyne/cm2, 0-24 h), F-actin filaments were mainly observed as stress fibers. After 24 h exposure, the fluorescence intensity of rhodamine-phalloidin-stained cells was enhanced, indicating the increase in F-actin content. It was suggested that not only F-actin distribution but also the content may be affected by shear stress at the early stage of exposure.

Original languageEnglish
Pages (from-to)121-125
Number of pages5
JournalFrontiers of medical and biological engineering : the international journal of the Japan Society of Medical Electronics and Biological Engineering
Volume5
Issue number2
Publication statusPublished - 1993

ASJC Scopus subject areas

  • Biophysics

Fingerprint Dive into the research topics of 'Time course changes in cytoskeletal structures of cultured endothelial cells exposed to shear stress.'. Together they form a unique fingerprint.

Cite this