Abstract
Changes in patterns of microfilament distribution were analyzed using cultured porcine aortic endothelial cells under shear flow. Within the elongated endothelial cells after shear flow exposure (20 dyne/cm2, 0-24 h), F-actin filaments were mainly observed as stress fibers. After 24 h exposure, the fluorescence intensity of rhodamine-phalloidin-stained cells was enhanced, indicating the increase in F-actin content. It was suggested that not only F-actin distribution but also the content may be affected by shear stress at the early stage of exposure.
| Original language | English |
|---|---|
| Pages (from-to) | 121-125 |
| Number of pages | 5 |
| Journal | Frontiers of medical and biological engineering : the international journal of the Japan Society of Medical Electronics and Biological Engineering |
| Volume | 5 |
| Issue number | 2 |
| Publication status | Published - 1993 |
ASJC Scopus subject areas
- Biophysics