Tightening and Loosening of the Abutment Screw Negatively Affects Implant Osseointegration in the Early Healing Stage in Rat Tibiae

Kenta Shobara, Toru Ogawa, Ratri M. Sitalaksmi, Akiyo Ito, Makiko Miyashita, Aya Shibamoto, Keiichi Sasaki

Research output: Contribution to journalArticlepeer-review

Abstract

PURPOSE: To examine the effect of tightening and loosening the dental implant screw on implant osseointegration in an elderly rat model. MATERIALS AND METHODS: Titanium dental implants were inserted in the bilateral tibiae of 34 elderly Wistar rats (1 year and 3 months old). Rats were randomly divided into five groups: control (no loading); immediate loading (IL) (vertical load [3 Hz for 15 minutes/day] immediately after implantation); early loading (EL) (load started on postoperative day 7); five times abutment removal (R5) (tightening and loosening of the abutment screw once per day for 5 days each week); and two times abutment screw removal (R2) (tightening and loosening of the abutment screw once per day for 2 days each week). After 4 weeks, the rats were euthanized, and the bone structure surrounding the dental implants was evaluated using microcomputed tomography analysis. RESULTS: Osseointegration failed more frequently in the EL, R2, and R5 groups than in the control and IL groups (P = .06). The EL, R2, and R5 groups also tended to have lower relative gray values than the control and IL groups. CONCLUSION: Tightening and loosening the abutment screw might negatively affect dental implant osseointegration in the early healing stage in older adults.

Original languageEnglish
Pages (from-to)199-203
Number of pages5
JournalThe International journal of prosthodontics
Volume34
Issue number2
DOIs
Publication statusPublished - 2021 Mar 1

ASJC Scopus subject areas

  • Oral Surgery

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