THz imaging of nucleobases and cancerous tissue using a GaP THz-wave generator

Jun Ichi Nishizawa, Tetsuo Sasaki, Ken Suto, Tetsuya Yamada, Tadao Tanabe, Takenori Tanno, Takashi Sawai, Yasuhiro Miura

Research output: Contribution to journalArticle

89 Citations (Scopus)

Abstract

We constructed a terahertz (THz) spectroscopic imaging system using a GaP THz-wave generator with automatic scanning control, and demonstrated power-transmission imaging measurements. To characterize the system, images of polyethylene pellets containing cytosine powder at various concentrations were taken. At a resonance frequency of 2.86 THz, the imaging system detected 5000 ppm cytosine. In addition, we demonstrated that THz imaging has a possibility to distinguish regions of metastatic cancer from normal tissue in liver, by comparing a THz-wave image at 0.835 THz with that at 1.465 THz.

Original languageEnglish
Pages (from-to)469-474
Number of pages6
JournalOptics Communications
Volume244
Issue number1-6
DOIs
Publication statusPublished - 2005 Jan 3

Keywords

  • Cancer liver
  • Cytosine
  • Frequency-tunable coherent terahertz wave
  • Terahertz imaging
  • Terahertz spectroscopy

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Atomic and Molecular Physics, and Optics
  • Physical and Theoretical Chemistry
  • Electrical and Electronic Engineering

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    Nishizawa, J. I., Sasaki, T., Suto, K., Yamada, T., Tanabe, T., Tanno, T., Sawai, T., & Miura, Y. (2005). THz imaging of nucleobases and cancerous tissue using a GaP THz-wave generator. Optics Communications, 244(1-6), 469-474. https://doi.org/10.1016/j.optcom.2004.09.064