[Thymic carcinoid associated with multiple endocrine neoplasia type 1].

Itaru Ishida, Hiroyuki Oura, Hiromichi Niikawa, Ken Onodera, Masashi Handa, Koji Onuki, Minoru Kawamura

Research output: Contribution to journalArticlepeer-review

Abstract

We report a case of a thymic carcinoid associated with multiple endocrine neoplasia type 1( MEN-1). A 37-year-old man was referred to our hospital for further examination of an abnormal chest shadow. A chest computed tomography (CT) showed an anterior mediastinal mass measuring 6.5 cm in diameter. A pathological diagnosis of thymic carcinoid was made from a CT-guided needle biopsy specimen. Preoperative workup including endocrinological examination revealed a pituitary adenoma and hyperparathyroidism, and MEN-1 was clinically diagnosed. We performed total parathyroidectomy with autotransplantation and thymectomy with lymph node dissection through cervical collar incision and median sternotomy. The diagnosis of MEN-1 was confirmed by the genomic analysis postoperatively. Since 25% of thymic carcinoids are MEN-1 related and 95% of MEN-1 patients develop hyperparathyroidism, it should be kept in mind that this condition can be treated by thymectomy and concurrent parathyroidectomy.

Original languageEnglish
Pages (from-to)466-469
Number of pages4
JournalKyobu geka. The Japanese journal of thoracic surgery
Volume65
Issue number6
Publication statusPublished - 2012 Jun
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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