Thrombotic microangiopathy presenting with a considerable accumulation of ascites: A case report

Tsuyoshi Shirai, Tomonori Ishii, Ryu Watanabe, Yumi Tajima, Hiroshi Fujii, Naruhiko Takasawa, Hiroshi Sato, Hideos Harigae

Research output: Contribution to journalArticlepeer-review

Abstract

A 46-year-old man presented with fever, thrombocytopenia, and a considerable accumulation of ascites. Although prednisolone and intravenous cyclophosphamide pulse (IVCY) were effective, he experienced recurrence. Renal insufficiency and hemolytic anemia developed subsequently. Schistocytes, negative Coombs' test, and elevated lactate dehydrogenase levels indicated thrombotic microangiopathy (TMA). He recovered well after receiving plasma infusion, IVCY, and prednisolone. Renal biopsy revealed subendothelial widening, thereby confirming TMA. This is a very rare case of TMA that presented with a considerable volume of ascites.

Original languageEnglish
Pages (from-to)53-57
Number of pages5
JournalInternal Medicine
Volume50
Issue number1
DOIs
Publication statusPublished - 2011

Keywords

  • Ascites
  • Renal biopsy
  • Thrombocytopenia
  • Thrombotic microangiopathy

ASJC Scopus subject areas

  • Internal Medicine

Fingerprint Dive into the research topics of 'Thrombotic microangiopathy presenting with a considerable accumulation of ascites: A case report'. Together they form a unique fingerprint.

Cite this