Three new taxanes with the 10-alkoxy group from the heartwood of Taxus cuspidata

Mei Dong, Man Li Zhang, Yu Fang Wang, Xi Ping Zhang, Cun Fang Li, Qing Wen Shi, Bin Cong, Hiromasa Kiyota

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

Three novel taxanes with the 10-alkoxy group were isolated from heartwood of Taxus cuspidata. The structures were identified as 2α,14β- diacetoxy-10β-ethoxytaxa-11,4(20)-dien-5α-ol (1), 2α,14β-diacetoxy-10β-methoxytaxa-11,4(20)-dien-5α-ol (2), and 2α-acetoxy-10β-ethoxytaxa-11,4(20)-diene-5α,14β-diol (3) on the basis of spectroscopic analysis. These are the first taxanes with an alkoxy moiety on the skeleton.

Original languageEnglish
Pages (from-to)2087-2090
Number of pages4
JournalBioscience, Biotechnology and Biochemistry
Volume71
Issue number8
DOIs
Publication statusPublished - 2007

Keywords

  • Alkoxy taxanes
  • Taxaceae
  • Taxane
  • Taxus cuspidata
  • Yew

ASJC Scopus subject areas

  • Biotechnology
  • Analytical Chemistry
  • Biochemistry
  • Applied Microbiology and Biotechnology
  • Molecular Biology
  • Organic Chemistry

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