Three-dimensional ultrasound imaging of regenerated skin with high frequency ultrasound

Yoshifumi Saijo, Yoshihiro Hagiwara, Kazuto Kobayashi, Nagaya Okada, Akira Tanaka, Naohiro Hozumi, Takahiro Iwamoto

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Citations (Scopus)

Abstract

Regenerated skin with complete organ structure is desired for the treatment of large burn and for the plastic surgery. High frequency ultrasound is suitable for nondestructive testing of such skin models because it can obtain both morphological and biomechanical information in non-invasive manner. A specially developed acoustic microscope system with the central frequency of 100 MHz was developed for evaluation of regenerated skin. The system was capable of (1) conventional C-mode acoustic microscope imaging of thinly sliced tissue, (2) ultrasound impedance in vivo imaging of the surface of tissue and (3) 3D ultrasound imaging of in vivo tissue. Sound speed in C-mode showed higher values at the area of dense fibroblasts in collagen sponge. The system can be used as the in vitro nondestructive evaluation tool in the process of regenerating skin and as the in vivo diagnostic system after implantation of the skin.

Original languageEnglish
Title of host publication2008 5th IEEE International Symposium on Biomedical Imaging
Subtitle of host publicationFrom Nano to Macro, Proceedings, ISBI
Pages1231-1234
Number of pages4
DOIs
Publication statusPublished - 2008 Sep 10
Event2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI - Paris, France
Duration: 2008 May 142008 May 17

Publication series

Name2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, Proceedings, ISBI

Other

Other2008 5th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI
CountryFrance
CityParis
Period08/5/1408/5/17

Keywords

  • Acoustic microscopy
  • Component
  • Signal processing
  • Skin
  • Speed measurement

ASJC Scopus subject areas

  • Biomedical Engineering

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