Three-dimensional structure of fucosyllactoses in an aqueous solution

Yasuko Ishizuka, Tadashi Nemoto, Masako Fujiwara, Ken Ichi Fujita, Hiroshi Nakanishi

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)


1H and 13C NMR spectra of four fucosyllactoses were analyzed and interresidual NOEs were detected in solution. Several interresidual NOE cross peaks between non-direct-bonding pyranoses were obtained in common with trisaccharides including fucose. Three-dimensional (3D) structures of the four saccharides were simulated with DADAS90 software using distance constraints estimated by NOE intensity. Results suggest approximate C2 rotating symmetry in the 3D 3,2′-difucosyllactose structure.

Original languageEnglish
Pages (from-to)523-533
Number of pages11
JournalJournal of Carbohydrate Chemistry
Issue number5
Publication statusPublished - 1999
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry


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