Three-dimensional behavior reproduction of microbubbles in flow under local ultrasound exposure

Kohji Masuda, Takumi Ito, Ren Koda, Naoto Hosaka, Takashi Mochizuki

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We have researched to control microbubbles in blood vessel by use of the acoustic radiation force for efficient and lower adverse effects medical treatments. However, behavior of microbubbles under the ultrasound exposure is complicated because of many kinds of parameters. In addition blood vessel network in human body is not simple. From these reasons, it is important to estimate emission condition of ultrasound. Therefore, numerical simulation model of microbubbles in flow is introduced. By concerning flow and ultrasound conditions, we have constructed a three-dimensional simulation to reproduce behavior of microbubbles using finite element method (FEM). As the results, the simulation showed good coincidences to the result of experiments in lower frequency, however, radius change of microbubbles and acoustic force perpendicular to the propagation direction should be considered in higher frequency.

Original languageEnglish
Title of host publicationBMEiCON 2013 - 6th Biomedical Engineering International Conference
DOIs
Publication statusPublished - 2013 Dec 1
Event6th Biomedical Engineering International Conference, BMEiCON 2013 - Krabi, Thailand
Duration: 2013 Oct 232013 Oct 25

Publication series

NameBMEiCON 2013 - 6th Biomedical Engineering International Conference

Other

Other6th Biomedical Engineering International Conference, BMEiCON 2013
CountryThailand
CityKrabi
Period13/10/2313/10/25

Keywords

  • Acoustic radiation force
  • Bloodvessel
  • Finite element method
  • Flow velocity
  • Microbubble
  • Simulation

ASJC Scopus subject areas

  • Biomedical Engineering

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  • Cite this

    Masuda, K., Ito, T., Koda, R., Hosaka, N., & Mochizuki, T. (2013). Three-dimensional behavior reproduction of microbubbles in flow under local ultrasound exposure. In BMEiCON 2013 - 6th Biomedical Engineering International Conference [6687716] (BMEiCON 2013 - 6th Biomedical Engineering International Conference). https://doi.org/10.1109/BMEiCon.2013.6687716