Thieme Chemistry Journals Awardees - Where Are They Now? Rhodium-Catalyzed Synthesis of Unsymmetric Di(heteroaryl) Ethers Using Heteroaryl Exchange Reaction

Saori Tanii; Mieko Arisawa; Takaya Tougo; Kiyofumi Horiuchi; Masahiko Yamaguchi

doi:10.1055/s-0036-1588801

Thieme Chemistry Journals Awardees - Where Are They Now? Rhodium-Catalyzed Synthesis of Unsymmetric Di(heteroaryl) Ethers Using Heteroaryl Exchange Reaction

Saori Tanii, Mieko Arisawa, Takaya Tougo, Kiyofumi Horiuchi, Masahiko Yamaguchi

PHA - Molecular Pharmaceutical Science

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

Unsymmetric di(heteroaryl) ethers were synthesized by the rhodium-catalyzed heteroaryl exchange reaction of heteroaryl aryl ethers and heteroaryl esters at equilibrium. Diverse unsymmetric di(heteroaryl) ethers containing five- and six-membered heteroarenes were obtained. Di(heteroaryl) ethers can be synthesized starting from diaryl ethers, because heteroaryl aryl ethers are obtained by the heteroaryl exchange reaction of diaryl ethers.

Original language	English
Pages (from-to)	1601-1607
Number of pages	7
Journal	Synlett
Volume	28
Issue number	13
DOIs	https://doi.org/10.1055/s-0036-1588801
Publication status	Published - 2017 Aug 14

Keywords

C-O bond cleavage
heteroaryl benzoates
heteroaryl exchange reaction
rhodium
unsymmetric di(heteroaryl) ethers

ASJC Scopus subject areas

Organic Chemistry

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10.1055/s-0036-1588801

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title = "Thieme Chemistry Journals Awardees - Where Are They Now? Rhodium-Catalyzed Synthesis of Unsymmetric Di(heteroaryl) Ethers Using Heteroaryl Exchange Reaction",

abstract = "Unsymmetric di(heteroaryl) ethers were synthesized by the rhodium-catalyzed heteroaryl exchange reaction of heteroaryl aryl ethers and heteroaryl esters at equilibrium. Diverse unsymmetric di(heteroaryl) ethers containing five- and six-membered heteroarenes were obtained. Di(heteroaryl) ethers can be synthesized starting from diaryl ethers, because heteroaryl aryl ethers are obtained by the heteroaryl exchange reaction of diaryl ethers.",

keywords = "C-O bond cleavage, heteroaryl benzoates, heteroaryl exchange reaction, rhodium, unsymmetric di(heteroaryl) ethers",

author = "Saori Tanii and Mieko Arisawa and Takaya Tougo and Kiyofumi Horiuchi and Masahiko Yamaguchi",

note = "Funding Information: This research was supported by the Platform Project for Supporting Drug Discovery and Life Science Research (Platform for Drug Discovery, Informatics, and Structural Life Science) from the Japan Agency for Medical Research and Development (AMED) and JSPS KAKENHI Grant Number JP15H00911. Publisher Copyright: {\textcopyright} 2017 Georg Thieme Verlag KG Stuttgart · New York.",

year = "2017",

month = aug,

day = "14",

doi = "10.1055/s-0036-1588801",

language = "English",

volume = "28",

pages = "1601--1607",

journal = "Synlett",

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publisher = "Georg Thieme Verlag",

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T1 - Thieme Chemistry Journals Awardees - Where Are They Now? Rhodium-Catalyzed Synthesis of Unsymmetric Di(heteroaryl) Ethers Using Heteroaryl Exchange Reaction

AU - Tanii, Saori

AU - Arisawa, Mieko

AU - Tougo, Takaya

AU - Horiuchi, Kiyofumi

AU - Yamaguchi, Masahiko

N1 - Funding Information: This research was supported by the Platform Project for Supporting Drug Discovery and Life Science Research (Platform for Drug Discovery, Informatics, and Structural Life Science) from the Japan Agency for Medical Research and Development (AMED) and JSPS KAKENHI Grant Number JP15H00911. Publisher Copyright: © 2017 Georg Thieme Verlag KG Stuttgart · New York.

PY - 2017/8/14

Y1 - 2017/8/14

N2 - Unsymmetric di(heteroaryl) ethers were synthesized by the rhodium-catalyzed heteroaryl exchange reaction of heteroaryl aryl ethers and heteroaryl esters at equilibrium. Diverse unsymmetric di(heteroaryl) ethers containing five- and six-membered heteroarenes were obtained. Di(heteroaryl) ethers can be synthesized starting from diaryl ethers, because heteroaryl aryl ethers are obtained by the heteroaryl exchange reaction of diaryl ethers.

AB - Unsymmetric di(heteroaryl) ethers were synthesized by the rhodium-catalyzed heteroaryl exchange reaction of heteroaryl aryl ethers and heteroaryl esters at equilibrium. Diverse unsymmetric di(heteroaryl) ethers containing five- and six-membered heteroarenes were obtained. Di(heteroaryl) ethers can be synthesized starting from diaryl ethers, because heteroaryl aryl ethers are obtained by the heteroaryl exchange reaction of diaryl ethers.

KW - C-O bond cleavage

KW - heteroaryl benzoates

KW - heteroaryl exchange reaction

KW - rhodium

KW - unsymmetric di(heteroaryl) ethers

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DO - 10.1055/s-0036-1588801

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SP - 1601

EP - 1607

JO - Synlett

JF - Synlett

SN - 0936-5214

IS - 13

ER -

Thieme Chemistry Journals Awardees - Where Are They Now? Rhodium-Catalyzed Synthesis of Unsymmetric Di(heteroaryl) Ethers Using Heteroaryl Exchange Reaction

Abstract

Keywords

ASJC Scopus subject areas

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