Thermo-responsive hydrogels with nanodomains: Rapid shrinking of a nanogel-crosslinking hydrogel of poly(N-isopropyl acrylamide)

Nobuyuki Morimoto, Takafumi Ohki, Kimio Kurita, Kazunari Akiyoshi

Research output: Contribution to journalArticlepeer-review

55 Citations (Scopus)

Abstract

Rapidly shrinking poly(N-isopropyl acrylamide) (PNIPAM) hydrogels are prepared by crosslinking with self-assembled nanogels that consist of cholesteryl- and methacryloyl-substituted pullulan (CHPMA). The CHPMA nanogel (Rh = 26.4 nm) was used as a crosslinker for a hydrophilic nanodomain. Transmission electron microscopy images of the nanogel-crosslinked PNI-PAM hydrogel reveal a well-defined nanoporous structure. The nanogel-crosslinked PNIPAM hydrogel shows rapid shrinking based on its structure. The shrinking half-time was ≈2 min, which is about 3400 times faster than that of a PNIPAM hydrogel crosslinked by methylene(bisacrylamide).

Original languageEnglish
Pages (from-to)672-676
Number of pages5
JournalMacromolecular Rapid Communications
Volume29
Issue number8
DOIs
Publication statusPublished - 2008 Apr 18
Externally publishedYes

Keywords

  • Hydrogels
  • N-isopropylacrylamide
  • Rapidly shrinking
  • Self-assembled nanogels
  • Stimuli-sensitive polymers

ASJC Scopus subject areas

  • Organic Chemistry
  • Polymers and Plastics
  • Materials Chemistry

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