Thermo-responsive hydrogels with nanodomains: Rapid shrinking of a nanogel-crosslinking hydrogel of poly(N-isopropyl acrylamide)

Nobuyuki Morimoto; Takafumi Ohki; Kimio Kurita; Kazunari Akiyoshi

doi:10.1002/marc.200700864

Thermo-responsive hydrogels with nanodomains: Rapid shrinking of a nanogel-crosslinking hydrogel of poly(N-isopropyl acrylamide)

Nobuyuki Morimoto, Takafumi Ohki, Kimio Kurita, Kazunari Akiyoshi

Research output: Contribution to journal › Article › peer-review

55 Citations (Scopus)

Abstract

Rapidly shrinking poly(N-isopropyl acrylamide) (PNIPAM) hydrogels are prepared by crosslinking with self-assembled nanogels that consist of cholesteryl- and methacryloyl-substituted pullulan (CHPMA). The CHPMA nanogel (R_h = 26.4 nm) was used as a crosslinker for a hydrophilic nanodomain. Transmission electron microscopy images of the nanogel-crosslinked PNI-PAM hydrogel reveal a well-defined nanoporous structure. The nanogel-crosslinked PNIPAM hydrogel shows rapid shrinking based on its structure. The shrinking half-time was ≈2 min, which is about 3400 times faster than that of a PNIPAM hydrogel crosslinked by methylene(bisacrylamide).

Original language	English
Pages (from-to)	672-676
Number of pages	5
Journal	Macromolecular Rapid Communications
Volume	29
Issue number	8
DOIs	https://doi.org/10.1002/marc.200700864
Publication status	Published - 2008 Apr 18
Externally published	Yes

Keywords

Hydrogels
N-isopropylacrylamide
Rapidly shrinking
Self-assembled nanogels
Stimuli-sensitive polymers

ASJC Scopus subject areas

Organic Chemistry
Polymers and Plastics
Materials Chemistry

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10.1002/marc.200700864

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abstract = "Rapidly shrinking poly(N-isopropyl acrylamide) (PNIPAM) hydrogels are prepared by crosslinking with self-assembled nanogels that consist of cholesteryl- and methacryloyl-substituted pullulan (CHPMA). The CHPMA nanogel (Rh = 26.4 nm) was used as a crosslinker for a hydrophilic nanodomain. Transmission electron microscopy images of the nanogel-crosslinked PNI-PAM hydrogel reveal a well-defined nanoporous structure. The nanogel-crosslinked PNIPAM hydrogel shows rapid shrinking based on its structure. The shrinking half-time was ≈2 min, which is about 3400 times faster than that of a PNIPAM hydrogel crosslinked by methylene(bisacrylamide).",

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T2 - Rapid shrinking of a nanogel-crosslinking hydrogel of poly(N-isopropyl acrylamide)

AU - Morimoto, Nobuyuki

AU - Ohki, Takafumi

AU - Kurita, Kimio

AU - Akiyoshi, Kazunari

PY - 2008/4/18

Y1 - 2008/4/18

N2 - Rapidly shrinking poly(N-isopropyl acrylamide) (PNIPAM) hydrogels are prepared by crosslinking with self-assembled nanogels that consist of cholesteryl- and methacryloyl-substituted pullulan (CHPMA). The CHPMA nanogel (Rh = 26.4 nm) was used as a crosslinker for a hydrophilic nanodomain. Transmission electron microscopy images of the nanogel-crosslinked PNI-PAM hydrogel reveal a well-defined nanoporous structure. The nanogel-crosslinked PNIPAM hydrogel shows rapid shrinking based on its structure. The shrinking half-time was ≈2 min, which is about 3400 times faster than that of a PNIPAM hydrogel crosslinked by methylene(bisacrylamide).

AB - Rapidly shrinking poly(N-isopropyl acrylamide) (PNIPAM) hydrogels are prepared by crosslinking with self-assembled nanogels that consist of cholesteryl- and methacryloyl-substituted pullulan (CHPMA). The CHPMA nanogel (Rh = 26.4 nm) was used as a crosslinker for a hydrophilic nanodomain. Transmission electron microscopy images of the nanogel-crosslinked PNI-PAM hydrogel reveal a well-defined nanoporous structure. The nanogel-crosslinked PNIPAM hydrogel shows rapid shrinking based on its structure. The shrinking half-time was ≈2 min, which is about 3400 times faster than that of a PNIPAM hydrogel crosslinked by methylene(bisacrylamide).

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KW - Rapidly shrinking

KW - Self-assembled nanogels

KW - Stimuli-sensitive polymers

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Thermo-responsive hydrogels with nanodomains: Rapid shrinking of a nanogel-crosslinking hydrogel of poly(N-isopropyl acrylamide)

Abstract

Keywords

ASJC Scopus subject areas

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