TY - JOUR
T1 - The very low density lipoprotein receptor. A second lipoprotein receptor that may mediate uptake of fatty acids into muscle and fat cells
AU - Yamamoto, Tokuo
AU - Takahashi, Sadao
AU - Sakai, Juro
AU - Kawarabayasi, Yutaka
PY - 1993/1/1
Y1 - 1993/1/1
N2 - The isolation of a cDNA highly homologous to that of the low-density lipoprotein (LDL) receptor revealed the presence of a lipoprotein receptor that specifically binds apolipoprotein-E-containing lipoproteins, including very low density lipoprotein (VLDL), intermediate-density lipoprotein, and β-migrating VLDL. This new receptor, designated VLDL receptor, consists of five domains that resemble those of the LDL receptor. The VLDL receptor mRNA is abundant in tissues performing active fatty acid metabolism, suggesting that the receptor may be responsible for the uptake of fatty acids in triglyceride-rich lipoproteins into muscle and fat cells.
AB - The isolation of a cDNA highly homologous to that of the low-density lipoprotein (LDL) receptor revealed the presence of a lipoprotein receptor that specifically binds apolipoprotein-E-containing lipoproteins, including very low density lipoprotein (VLDL), intermediate-density lipoprotein, and β-migrating VLDL. This new receptor, designated VLDL receptor, consists of five domains that resemble those of the LDL receptor. The VLDL receptor mRNA is abundant in tissues performing active fatty acid metabolism, suggesting that the receptor may be responsible for the uptake of fatty acids in triglyceride-rich lipoproteins into muscle and fat cells.
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U2 - 10.1016/1050-1738(93)90015-X
DO - 10.1016/1050-1738(93)90015-X
M3 - Short survey
C2 - 21244941
AN - SCOPUS:0027161021
VL - 3
SP - 144
EP - 148
JO - Trends in Cardiovascular Medicine
JF - Trends in Cardiovascular Medicine
SN - 1050-1738
IS - 4
ER -