The vasoactive systems in the regulation of renal hemodynamics

Ryo Morimoto, Sadayoshi Ito

Research output: Contribution to journalReview articlepeer-review


In the homeostasis of sodium and water metabolism, the kidney plays a pivotal role. It is the center of multiple humoral systems, such as renin angiotensin aldosterone system, arginine vasopressin, atrial natriuretic peptide, and nitric oxide, which control both systemic and renal circulation in concert. Disturbances in these systems secondary to cardiovascular compromise, especially hemodynamic insufficiency in renal circulation, lead to the accumulation of excess sodium and water, resulting in edema formation. So it is crucial to elucidate the relationship between the kidney and these vasoactive systems for the better understanding of pathophysiology of edema and volume retension.

Original languageEnglish
Pages (from-to)64-67
Number of pages4
JournalNippon rinsho. Japanese journal of clinical medicine
Issue number1
Publication statusPublished - 2005 Jan

ASJC Scopus subject areas

  • Medicine(all)


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