The ultrasonic properties of gastric cancer tissues obtained with a scanning acoustic microscope system

Yoshifumi Saijo, Motonao Tanaka, Hiroaki Okawai, Floyd Dunn

Research output: Contribution to journalArticlepeer-review

64 Citations (Scopus)

Abstract

A newly developed scanning acoustic microscope (SAM) system operating in the frequency range of 100-200 MHz has been employed to measure the attenuation and the sound speed of formalin-fixed specimens of five different types of gastric cancer. Signet-ring cell carcinoma specimens exhibit attenuation constant and sound speed values significantly lower than other types of gastric cancer tissues. Tubular adenocarcinoma specimens exhibit a trend toward higher attenuation and sound speed values as the cell type become differentiated. Our measurements and observations suggest that the ultrasonic properties are influenced by cellular arrangement, intercellular junction and intracellular chemical components.

Original languageEnglish
Pages (from-to)709-714
Number of pages6
JournalUltrasound in Medicine and Biology
Volume17
Issue number7
DOIs
Publication statusPublished - 1991
Externally publishedYes

Keywords

  • Attenuation constant
  • Gastric cancer
  • Scanning acoustic microscope
  • Sound speed
  • Ultrasonic tissue characterization

ASJC Scopus subject areas

  • Biophysics
  • Radiological and Ultrasound Technology
  • Acoustics and Ultrasonics

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