The surface characterization and bioactivity of NANOZR in vitro

Jian Min Han, Guang Hong, Hiroyuki Matsui, Yoshinaka Shimizu, Gang Zheng, Hong Lin, Keiichi Sasaki

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

The purpose of this study was to evaluate the surface characterization and bioactivity of ceria-stabilized zirconia/alumina nanocomposite (NANOZR) in comparison to yttria-stabilized zirconia (3Y-TZP) and pure titanium (CpTi). Three-dimension surface morphology, surface wettability, bovine serum albumin adsorption rate, cell morphology, cell proliferation and ALP activity of three tested materials were measured. There were no significant differences in surface roughness, contact angle among the three materials. The ALP expression of NANOZR was higher than CpTi and 3Y-TZP at 14 and 21 days although bovine serum albumin adsorption rate, cell morphology; and cell proliferation was not different among the three materials. These results suggest that the three test materials basically had similar surface characterization and bioactivity. Within the limitations of this study, our results show that the three test materials were biologically similar bio-inert materials.

Original languageEnglish
Pages (from-to)210-219
Number of pages10
JournalDental materials journal
Volume33
Issue number2
DOIs
Publication statusPublished - 2014

Keywords

  • Bioactivity
  • MC3T3
  • NANOZR
  • Surface characterization

ASJC Scopus subject areas

  • Ceramics and Composites
  • Dentistry(all)

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