Abstract
The Diels-Alder reaction of 5-methyl-2-cyclohexene-1-one (I) with butadiene was examined. It was concluded that addition of butadiene to the dienophile (I) took place from the opposite side to a secondary methyl side to give initially the cis adduct (IIb), which then epimerizes mostly to the trans derivative (IIa).
Original language | English |
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Pages (from-to) | 2784-2787 |
Number of pages | 4 |
Journal | Chemical and Pharmaceutical Bulletin |
Volume | 22 |
Issue number | 12 |
DOIs | |
Publication status | Published - 1974 |
ASJC Scopus subject areas
- Chemistry(all)
- Drug Discovery