The significance of surgical treatment for T4 lung cancer

A. Sakurada, M. Sagawa, K. Usuda, A. Kanda, H. Aikawa, Y. Chen, O. Endo, H. Takahashi, S. Takahashi, M. Sato, Y. Saito, S. Fujimura

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7 Citations (Scopus)


A total of 114 pT4 patients underwent pulmonary resection from January 1980 to December 1993 at our hospital. The overall five-year survival rate of the 114 cases was 17%. There was no significance between the five-year survival rate of squamous cell carcinoma and that of adenocarcinoma. Five-year survival rates of 17 patients with N0 disease, 29 patients with N1 disease, 51 patients with N2 disease, 1 patients with N3 disease, and 16 patients with NX disease were 40%, 21%, 21%, 0%, and 0%, respectively. Five-year survival rate of 89 cases with single factor of T4 was 24% and that of 25 cases with more than one factor was 4% (0.05 < P < 0.1). In the patients with only single factor of T4, five-year survival rates of 6 patients with left atrium invasion, 13 patients with major vessel invasion, 9 patients with trachea/carina invasion, and 18 patients with vertebral body, were 50%, 38%, 22%, and 0%, respectively. Furthermore, in 38 pT4 patients with involvement only to single adjacent structure, five-year survival rates were 47% in curative operation (n = 17) and 10% in non-curative operation (n = 21) (P < 0.05). We conclude that surgical treatment for T4 lung cancer should be performed to patients with single structure invasion which is expected to have a curative operation. N0 disease is more favorable than N1 or N2 disease.

Original languageEnglish
Pages (from-to)95-100
Number of pages6
JournalKyobu geka. The Japanese journal of thoracic surgery
Issue number2
Publication statusPublished - 1997 Feb

ASJC Scopus subject areas

  • Medicine(all)


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