The Seiji Memorial Lecture - The melanosome: An ideal model to study cellular differentiation

Tsuneto Kushimoto, Julio C. Valencia, Gertrude E. Costin, Kazutomo Toyofuku, Hidenori Watabe, Ken-Ichi Yasumoto, Francois Rouzaud, Wilfred D. Vieira, Vincent J. Hearing

Research output: Contribution to journalArticle

66 Citations (Scopus)

Abstract

Melanosomes provide an intriguing model for study at many levels. In part this is due to their unique structure and function, but also in part to their involvement in pigmentary diseases and as a model to study basic cellular mechanisms of organelle biogenesis. Recent studies have elucidated the full proteome of the melanosome and the metabolic and molecular lesions involved in a number of pigmentary diseases have been resolved. This paper summarizes recent advances in the field in these areas.

Original languageEnglish
Pages (from-to)237-244
Number of pages8
JournalPigment Cell Research
Volume16
Issue number3
DOIs
Publication statusPublished - 2003 Jun 1
Externally publishedYes

Keywords

  • Biogenesis
  • Melanosome
  • Pigmentation
  • Proteomics

ASJC Scopus subject areas

  • Agronomy and Crop Science
  • Plant Science
  • Developmental Biology
  • Clinical Biochemistry
  • Cell Biology

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  • Cite this

    Kushimoto, T., Valencia, J. C., Costin, G. E., Toyofuku, K., Watabe, H., Yasumoto, K-I., Rouzaud, F., Vieira, W. D., & Hearing, V. J. (2003). The Seiji Memorial Lecture - The melanosome: An ideal model to study cellular differentiation. Pigment Cell Research, 16(3), 237-244. https://doi.org/10.1034/j.1600-0749.2003.00034.x