TY - JOUR
T1 - The RIKEN integrated database of mammals
AU - Masuya, Hiroshi
AU - Makita, Yuko
AU - Kobayashi, Norio
AU - Nishikata, Koro
AU - Yoshida, Yuko
AU - Mochizuki, Yoshiki
AU - Doi, Koji
AU - Takatsuki, Terue
AU - Waki, Kazunori
AU - Tanaka, Nobuhiko
AU - Ishii, Manabu
AU - Matsushima, Akihiro
AU - Takahashi, Satoshi
AU - Hijikata, Atsushi
AU - Kozaki, Kouji
AU - Furuichi, Teiichi
AU - Kawaji, Hideya
AU - Wakana, Shigeharu
AU - Nakamura, Yukio
AU - Yoshiki, Atsushi
AU - Murata, Takehide
AU - Fukami-Kobayashi, Kaoru
AU - Mohan, Sujatha
AU - Ohara, Osamu
AU - Hayashizaki, Yoshihide
AU - Mizoguchi, Riichiro
AU - Obata, Yuichi
AU - Toyoda, Tetsuro
N1 - Funding Information:
Maintenance of SciNetS is supported by the Integrated Database Project by Ministry of Education, Culture, Sports, Science and Technology (MEXT).
PY - 2011/1
Y1 - 2011/1
N2 - The RIKEN integrated database of mammals (http:// scinets.org/db/mammal) is the official undertaking to integrate its mammalian databases produced from multiple large-scale programs that have been promoted by the institute. The database integrates not only RIKEN's original databases, such as FANTOM, the ENU mutagenesis program, the RIKEN Cerebellar Development Transcriptome Database and the Bioresource Database, but also imported data from public databases, such as Ensembl, MGI and biomedical ontologies. Our integrated database has been implemented on the infrastructure of publication medium for databases, termed SciNetS/SciNeS, or the Scientists' Networking System, where the data and metadata are structured as a semantic web and are downloadable in various standardized formats. The top-level ontology-based implementation of mammal-related data directly integrates the representative knowledge and individual data records in existing databases to ensure advanced cross-database searches and reduced unevenness of the data management operations. Through the development of this database, we propose a novel methodology for the development of standardized comprehensive management of heterogeneous data sets in multiple databases to improve the sustainability, accessibility, utility and publicity of the data of biomedical information.
AB - The RIKEN integrated database of mammals (http:// scinets.org/db/mammal) is the official undertaking to integrate its mammalian databases produced from multiple large-scale programs that have been promoted by the institute. The database integrates not only RIKEN's original databases, such as FANTOM, the ENU mutagenesis program, the RIKEN Cerebellar Development Transcriptome Database and the Bioresource Database, but also imported data from public databases, such as Ensembl, MGI and biomedical ontologies. Our integrated database has been implemented on the infrastructure of publication medium for databases, termed SciNetS/SciNeS, or the Scientists' Networking System, where the data and metadata are structured as a semantic web and are downloadable in various standardized formats. The top-level ontology-based implementation of mammal-related data directly integrates the representative knowledge and individual data records in existing databases to ensure advanced cross-database searches and reduced unevenness of the data management operations. Through the development of this database, we propose a novel methodology for the development of standardized comprehensive management of heterogeneous data sets in multiple databases to improve the sustainability, accessibility, utility and publicity of the data of biomedical information.
UR - http://www.scopus.com/inward/record.url?scp=78651316616&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=78651316616&partnerID=8YFLogxK
U2 - 10.1093/nar/gkq1078
DO - 10.1093/nar/gkq1078
M3 - Article
C2 - 21076152
AN - SCOPUS:78651316616
VL - 39
SP - D861-D870
JO - Nucleic Acids Research
JF - Nucleic Acids Research
SN - 0305-1048
IS - SUPPL. 1
ER -