The resistance to acidic and alkaline environments of endodontic pathogen Enterococcus faecalis

K. Nakajo, Y. Iwami, R. Komori, S. Ishikawa, T. Ueno, Y. Suzuki, N. Takahashi

Research output: Contribution to journalReview articlepeer-review

4 Citations (Scopus)

Abstract

The aim of this study was to investigate the acid- and alkali-resistance and its biochemical mechanism of endodontic pathogen Enterococcus faecalis and to compare with those of other oral streptococci. The acid- and alkali-resistance of each strain was estimated as follows: 1) the growth ability in the complex medium, 2) the cell durability to leakage of pre-loaded BCECF and 3) the intracellular pH (pHin) stability. The results indicate that E. faecalis is not only acid-resistant similar to Streptococcus mutans but more alkali-resistant than S. mutans. This study suggests that the acid- and alkali-resistance of E. faecalis is derived from the membrane durability and impermeability against acid and alkali. Such characteristics of E. faecalis could be the reasons why E. faecalis is frequently isolated from both acidic caries lesions and persistent infected root canals where calcium hydroxide medicaments are ineffective.

Original languageEnglish
Pages (from-to)191-192
Number of pages2
JournalInternational Congress Series
Volume1284
DOIs
Publication statusPublished - 2005 Sep

Keywords

  • Acid-resistance
  • Alkali-resistance
  • E. faecalis
  • Endodontic pathogen

ASJC Scopus subject areas

  • Medicine(all)

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