The Posterior Nasal Nerve Plays an Important Role on Cardiopulmonary Reflexes to Nasal Application of Capsaicin, Distilled Water and l-Menthol in Anesthetized Dogs

Arata Kanamaru; Tatsushi Mutoh; Kentaro Kojima; Ryohei Nishimura; Nobuo Sasaki; Masayoshi Kuwahara; Hirokazu Tsubone

doi:10.1292/jvms.61.85

The Posterior Nasal Nerve Plays an Important Role on Cardiopulmonary Reflexes to Nasal Application of Capsaicin, Distilled Water and l-Menthol in Anesthetized Dogs

Arata Kanamaru, Tatsushi Mutoh, Kentaro Kojima, Ryohei Nishimura, Nobuo Sasaki, Masayoshi Kuwahara, Hirokazu Tsubone

Division of Brain Science

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

The sensory innervation of the cardiopulmonary reflexes to nasal application of capsaicin (CAPS), distilled water (DW) and l-menthol (LM) was studied in anesthetized dogs breathing through tracheostomy. A marked cardiopulmonary reflex was observed by CAPS and DW into the nasal cavity, while a prolongation of expiration was induced by LM. All these reflexes were significantly decreased by bilateral section of the posterior nasal nerve (PNN) and completely abolished by topical nasal anesthesia with lidocaine. Responses of the whole nerve activity of the PNN to these substances corresponded to the magnitude of the reflexes. These results indicate that PNN afferents play an important role on the reflex elicitation of the noxious, water and cold stimuli from the nasal cavity.

Original language	English
Pages (from-to)	85-88
Number of pages	4
Journal	Journal of Veterinary Medical Science
Volume	61
Issue number	1
DOIs	https://doi.org/10.1292/jvms.61.85
Publication status	Published - 1999 Jan

Keywords

Canine
Control of breathing
Trigeminal nerve afferent

ASJC Scopus subject areas

veterinary(all)

Access to Document

10.1292/jvms.61.85

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The Posterior Nasal Nerve Plays an Important Role on Cardiopulmonary Reflexes to Nasal Application of Capsaicin, Distilled Water and l-Menthol in Anesthetized Dogs. / Kanamaru, Arata; Mutoh, Tatsushi; Kojima, Kentaro; Nishimura, Ryohei; Sasaki, Nobuo; Kuwahara, Masayoshi; Tsubone, Hirokazu.

In: Journal of Veterinary Medical Science, Vol. 61, No. 1, 01.1999, p. 85-88.

Research output: Contribution to journal › Article › peer-review

Kanamaru, Arata ; Mutoh, Tatsushi ; Kojima, Kentaro ; Nishimura, Ryohei ; Sasaki, Nobuo ; Kuwahara, Masayoshi ; Tsubone, Hirokazu. / The Posterior Nasal Nerve Plays an Important Role on Cardiopulmonary Reflexes to Nasal Application of Capsaicin, Distilled Water and l-Menthol in Anesthetized Dogs. In: Journal of Veterinary Medical Science. 1999 ; Vol. 61, No. 1. pp. 85-88.

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abstract = "The sensory innervation of the cardiopulmonary reflexes to nasal application of capsaicin (CAPS), distilled water (DW) and l-menthol (LM) was studied in anesthetized dogs breathing through tracheostomy. A marked cardiopulmonary reflex was observed by CAPS and DW into the nasal cavity, while a prolongation of expiration was induced by LM. All these reflexes were significantly decreased by bilateral section of the posterior nasal nerve (PNN) and completely abolished by topical nasal anesthesia with lidocaine. Responses of the whole nerve activity of the PNN to these substances corresponded to the magnitude of the reflexes. These results indicate that PNN afferents play an important role on the reflex elicitation of the noxious, water and cold stimuli from the nasal cavity.",

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