The one-step preparation of sugar oxazoline enables the synthesis of glycoprotein having a definite structure

Masato Noguchi, Atsushi Kobayashi, Shin Ichiro Shoda

Research output: Contribution to journalReview articlepeer-review

4 Citations (Scopus)

Abstract

Sugar oxazoline derivatives are useful donor substrates for N-acetylglucosaminidase-catalyzed glycosylation reactions. In this review, we describe the direct conversion of free sugars to their oxazoline derivatives by using water-soluble dehydrating agents and its application to enzymatic synthesis of complex glycosidic compounds including glycoproteins.

Original languageEnglish
Pages (from-to)E35-E42
JournalTrends in Glycoscience and Glycotechnology
Volume27
Issue number158
DOIs
Publication statusPublished - 2015 Nov 25

Keywords

  • Dehydrating agent
  • Endo-N-acetyl glucosaminidase
  • Glycoprotein
  • Sugar oxazoline

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry

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