Abstract
The presence of a significant amount of 9,11-conjugated linoleic acid (CLA, 9,11-18:2) was confirmed in the liver and plasma lipids of rats fed a 1% (w/w % of diet) eleostearic acid (ESA, 9,11,13-18:3) diet for 4 wk. The chemical structure of the 9,11-CLA apparent in the tissue lipids was identified by gas chromatography-electron impact mass spectrometry after its conversion to a 4,4-dimethyloxazoline derivative. The concentration of CLA in the total fatty acids of the liver and plasma lipids reached to about 1% for each in the CLA-supplemented rats, while reaching 3,2% and 2.5%, respectively, in the ESA-supplemented rats. The results suggest that α-ESA is metabolized partially to CLA via a delta 13-saturation reaction in the rat. Some biological activities observed in α-ESA-fed animals may be ascribed also to CLA that is formed from ESA in the body.
| Original language | English |
|---|---|
| Pages (from-to) | 195-200 |
| Number of pages | 6 |
| Journal | Journal of nutritional science and vitaminology |
| Volume | 49 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 2003 Jun |
Keywords
- Conjugated fatty acid
- Conjugated linoleic acid
- Conjugated trienoic acid
- Eleostearic acid
- Tung oil
ASJC Scopus subject areas
- Medicine (miscellaneous)
- Nutrition and Dietetics