The mechanism responsible for hypertension in a patient with guillain-Barré syndrome

Naoyoshi Minami, Yutaka Imai, Yukio Miura, Keishi Abe

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

We report a case of hypertension associated with Guillain-Barré syndrome. In this case, the circadian variation of blood pressure was interrupted. Examination of neurohumoral factors revealed a hyperactive sympathetic nervous system and an increase in plasma renin activity. Clonidine, which acts centrally to inhibit sympathetic outflow, did not suppress serum norepinephrine or epinephrine. These observations suggest that autonomous hyperactivity of the efferent pathway of the sympathetic nervous system may cause the sustained hypertension throughout the day in this case.

Original languageEnglish
Pages (from-to)607-617
Number of pages11
JournalClinical and Experimental Hypertension
Volume17
Issue number4
DOIs
Publication statusPublished - 1995

ASJC Scopus subject areas

  • Internal Medicine
  • Physiology

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