The mechanical behavior and morphological structure of callus in experimental callotasis

Masamizu Ohyama, Yoshinori Miyasaka, Minoru Sakurai, A. Toshimitsu Yokobori, Shigeru Sasaki

    Research output: Contribution to journalArticlepeer-review

    20 Citations (Scopus)

    Abstract

    Experimental callotasis was made in rabbit femurs. In order to compare mechanical behaviors and morphological structure of callus in callotasis, mechanical tests and histological examination were performed. Twenty Japanese white male rabbits were used. The right femurs were osteotomized at the level of the midshaft with a rotary cutter and fixed with a mini-model external fixator. After a 5-day waiting period, bone lengthening was started at the rate of 0.25 mm two times a day. Animals were divided into four groups. Group 1 and Group 2 were continual distraction group, Group 3 and Group 4 discontinued distraction group. The viscoelastic property was demonstrated in continual distraction group irrespective of distraction period, we thought the central undifferentiated connective tissue in callus was mainly responsible for the mechanical behavior. On the other hand, in discontinued distraction group, viscoelastic property shifted to elastic property corresponding to the rest period, we thought this change of mechanical behavior was histologically owing to the replacement of undifferentiated connective tissue by cartilage and the partial union of bone in callus.

    Original languageEnglish
    Pages (from-to)273-281
    Number of pages9
    JournalBio-medical materials and engineering
    Volume4
    Issue number4
    DOIs
    Publication statusPublished - 1994

    Keywords

    • Callotasis
    • Callus
    • Histological examination
    • Mechanical test

    ASJC Scopus subject areas

    • Biomaterials
    • Biomedical Engineering

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