TY - JOUR
T1 - The levels of tetrodotoxin and its analogue 6-epitetrodotoxin in the red-spotted newt, Notophthalmus viridescens
AU - Yotsu-Yamashita, Mari
AU - Mebs, Dietrich
N1 - Funding Information:
We would like to thank Dr H.M. Wilbur, Mountain Lake Biological Station, University of Virginia, for providing the opportunity to collect the newts. This work was supported in part by a grant of Deutsche Forschungsgemeinschaft to D.M., by Grants-in Aid from the Ministry of Education, Science, Sports and Culture of Japan (12045210), from the Naito Foundation and the Fujisawa Foundation to M.Y.Y.
PY - 2001
Y1 - 2001
N2 - Tetrodotoxin (TTX) and its analogue 6-epiTTX were detected in 11-12 specimens of the red-spotted newt, Notophthalmus viridescens, by a post-column fluorescent-HPLC system and by LC/MS in selected ion monitoring mode. TTX levels varied considerably among individuals from low (less than 0.15 μg TTX/g newt) to high concentrations (23.5 μg TTX/g newt), while 6-epiTTX was found to be a minor constituent in all specimens.
AB - Tetrodotoxin (TTX) and its analogue 6-epiTTX were detected in 11-12 specimens of the red-spotted newt, Notophthalmus viridescens, by a post-column fluorescent-HPLC system and by LC/MS in selected ion monitoring mode. TTX levels varied considerably among individuals from low (less than 0.15 μg TTX/g newt) to high concentrations (23.5 μg TTX/g newt), while 6-epiTTX was found to be a minor constituent in all specimens.
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U2 - 10.1016/S0041-0101(00)00263-4
DO - 10.1016/S0041-0101(00)00263-4
M3 - Article
C2 - 11306140
AN - SCOPUS:0035071483
VL - 39
SP - 1261
EP - 1263
JO - Toxicon
JF - Toxicon
SN - 0041-0101
IS - 8
ER -