The inner blood-retinal barrier (inner BRB) is created by complex tight junctions of retinal capillary endothelial cells. Although this barrier prevents the free diffusion of substances between the circulating blood and the neural retina, the inner BRB efficiently supplies nutrients to the retina and removes endobiotics and xenobiotics from the retina to maintain a constant milieu in the neural retina. We review herein the molecular structure and transport mechanism at the inner BRB.
|Title of host publication||Biology and Regulation of Blood-Tissue Barriers|
|Publisher||Springer New York LLC|
|Number of pages||20|
|Publication status||Published - 2013|
|Name||Advances in Experimental Medicine and Biology|
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)