The inner blood-retinal barrier molecular structure and transport biology

Ken Ichi Hosoya, Masanori Tachikawa

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

The inner blood-retinal barrier (inner BRB) is created by complex tight junctions of retinal capillary endothelial cells. Although this barrier prevents the free diffusion of substances between the circulating blood and the neural retina, the inner BRB efficiently supplies nutrients to the retina and removes endobiotics and xenobiotics from the retina to maintain a constant milieu in the neural retina. We review herein the molecular structure and transport mechanism at the inner BRB.

Original languageEnglish
Title of host publicationAdvances in Experimental Medicine and Biology
PublisherSpringer New York LLC
Pages85-104
Number of pages20
Volume763
ISBN (Print)9781461447108
DOIs
Publication statusPublished - 2013
Externally publishedYes

Publication series

NameAdvances in Experimental Medicine and Biology
Volume763
ISSN (Print)00652598

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

Fingerprint Dive into the research topics of 'The inner blood-retinal barrier molecular structure and transport biology'. Together they form a unique fingerprint.

Cite this