The great east Japan earthquake: Blood pressure control in patients with chronic kidney disease

Kenichi Tanaka, Masaaki Nakayama, Yoshihiro Tani, Kimio Watanabe, Jun Asai, Yoshimitsu Hayashi, Koichi Asahi, Tsuyoshi Watanabe

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20 Citations (Scopus)


Background At 1446 on 11 March 2011, northeastern Japan was struck by a major earthquake measuring 9.0 on the Richter scale. There have been several reports of transient blood pressure increases after a major earthquake, but the impact of a major earthquake on blood pressure in chronic kidney disease (CKD) patients has not been fully investigated.MethodsChanges in clinic blood pressure following the earthquake were investigated in 132 hypertensive patients with stage 3 and 4 CKD who were residents of Fukushima City.ResultsBoth systolic and diastolic blood pressures were significantly elevated 1-3 weeks after the earthquake compared with before the earthquake (134 ± 19 mm Hg vs. 138 ± 20 mm Hg, P = 0.02 for systolic; 76 ± 13 mm Hg vs. 79 ± 12 mm Hg, P = 0.01 for diastolic), and these values returned to baseline by 5-7 weeks after the earthquake. Multiple logistic regression analysis identified male sex (odds ratio (OR), 0.35; 95% confidence interval (CI), 0.14-0.86; P = 0.02), mean blood pressure at baseline (OR, 0.92; 95% CI, 0.86-0.96; P < 0.01), and sympatholytic medications, such as α-blockers, β-blockers, or central sympatholytics (OR, 0.23; 95% CI, 0.07-0.76; P = 0.01), as independent factors related to elevation of mean blood pressure 1-3 weeks after the earthquake in CKD patients.ConclusionsBlood pressure was significantly increased after a major earthquake in hypertensive patients with stage 3 and 4 CKD. During the first 3 weeks after the earthquake, blood pressure control was associated with the use of sympatholytic medications.

Original languageEnglish
Pages (from-to)951-954
Number of pages4
JournalAmerican Journal of Hypertension
Issue number9
Publication statusPublished - 2012 Sep


  • blood pressure
  • chronic kidney disease
  • earthquake
  • hypertension
  • sympatholytics

ASJC Scopus subject areas

  • Internal Medicine


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